Somatotropin, also commonly referred to as human growth hormone (HGH), is a hormone that is produced in the human body and excreted into the blood by the somatotrope cells of the anterior pituitary gland. It is a single-chain protein that is composed of 191 amino acids with a molecular weight of approximately 22,000 Daltons.
GH secretion has many direct and indirect effects on the human body. First, GH stimulates the liver's production of insulin-like growth factor (IGH-1). Because GH stimulates the liver's production of IGF-1, the effects of both GH and IGF-1 are listed below.
Synthetic version of Human Growth Hormone is called Somatropin (191 amino acid sequence growth hormone). It is identical to human body's own GH. However that is not the case for Somatrem (192 amino acid sequence growth hormone). But we will talk about that later
Direct and Indirect Effects of Somatotropin on the Human Body
- Stimulates division and multiplication of the chondrocytes of cartilage
- Increases both calcium retention and the mineralization of bones
- Stimulates cell growth in every organ of a human body
- Increases metabolism
- Repairs damaged cells
- Induces protein synthesis
- Decreases protein degradation
- Stimulates the immune system
- Promotes lipolysis
- Increases glucose transport
In the human body, somatotropin is at its highest levels in children and during puberty, stimulating the growth of the body during those ages. After puberty, the level of growth hormone secretion declines and continues to do so as a person ages.
Growth hormone deficiency (GHD) is a condition in which a person's anterior pituitary gland fails to produce an adequate amount of normal endogenous growth hormone. In children, this results in short stature and growth failure. In adults, GHD causes deficiencies of strength, energy, and bone mass.
GHD can be treated in both children and adults with somatropin, also known as synthetic human growth hormone (HGH). However, to treat conditions of height, a child must be treated before the growth plates (epiphyses) at the ends of long bones have fully matured and closed.
Healthy adults most commonly use Human Growth Hormone for Anti Aging
, Body Building
and Fat Loss
As mentioned above, there are two different types of human growth hormone. One is Somatropin (the real HGH) and the other is Somatrem which is very close to real HGH. You can read more about it on HGH Types